![]() Retrospective study of 69 pts average age 9.9 ys all with neurodegenerative disease 81% with pre-existing swallowing abn "Use of ultrasound guidance during the injection procedure seems to improve efficacy and safety"ĭrooling associated with neurodevelopmental problems in children Improvement in both groups seen, but statistically greater with U/S guidance. Prospective study of 15 patients with Parkinson's disease - 8 treated with BTX-A with U/S guidance, 7 treated without ultrasound guidanceĭry dental rolls placed intraorally were weighed after being retained for 5 minutes subjective assessment scale (VAS = visual analog scale) daily assessment for 7 days after treatment U/S machine used 12 mHz linear transducer with 15 units BTX-A into two separate sites (upper and lower poles of parotid with 30 gauge needle ('total 30 U of BTX-A" identified as 15 units to each parotid gland). Ultrasound-guided versus 'blind' intraparotid injections ".botulinum toxin A has a longer duration of action and fewer systemic autonomic adverse effects, which suggests that it may be preferred for the management of sialorrhea." Conversion factor to equivalent units of botulinum toxin A (Botox) was 2.5:1 for Dysport and 50:1 for Myobloc of Neurobloc (botulinum toxin B). Meta-analysis of 8 studies showed botulinum toxin to significantly decrease the severity of drooling in patients with sialorrhea. “Botulinum toxin type B is effective in the management of postoperative sialocele after parotid gland surgery” Salivary sialocele after parotidectomy rx with aspiration and BtxBĬase report – sialocele after parotidectomy with 2500 mouse units of botulinum toxin type B in residual parotid gland tissue with repeated aspirations before and after BtxB injection Highly effective and relatively safe primary method, for the treatment of an acute Go to: Complication from open (transfacial) approach to parotid stone removalĬase report – two injections totaling 10 U BtxA on POD #1 after parotidectomy ‘disappearance of salivary fistula one day after injection” Salivary fistula after transparotid approach to parapharyngeal tumor Promising use of Botox, ultrasound and sialendoscopy to replace traditional invasive tx of sialocoeles ‘First case of Iatrogenic postop smg sialocoele and first use of Btx for that purpose’ (successful)Īfter unsuccessful surgery to remove stone in distal 1/3 of Stensen’s duct with success ultimately with lithotripsyĬase report – aspirate fluid – U/S guided injection 50 U Btx A subsequent series of two sialendoscopies *“Botulinum toxin-A can also be effectively used to reduce the bulk of an enlarged parotid gland without affecting saliva production.”Īfter SMG resection for stone with residual gland left behindĬase report – aspirate fluid – U/S guided 3 separate injections (total 30 U BtxA) Highly efficacious and cost effective, nonsurgical option for reducing the width and shape of the lower face and jawline.” (average initial does to masseter is 40 units Btx-A repeated twice at one month intervals.) Parotid injections done to address ‘bull necked’ look with 40 units of Botox injected into the parotid gland monthly until the swelling becomes less obvious (usually 3-4 sessions “no complaints of dryness of mouth or decrease in saliva production” Repeat injections until no palpable masseter muscle activity and ramus of mandible felt. Historical description of authors use beginning in 1998 to treat over 600 patients with wide ‘boxy’ face or ‘square jaws”. *Btx may be used as a new treatment for lower face contouring.Īdjunctive parotid instillation of Botox to supplement more standard masseter injection for ‘facial slimming”Ĭase Presentation Use of Botulinum Toxin Following Partial Submandibular Gland Resection (repeated two subsequent injections at two month intervals used same 20 units to each SMG with slightly lower dose to parotids - 32 U to each parotid (2nd time) and 28 U to each parotid (3rd time) Induce atrophy of prominent salivary glandsįirst case: 30 U (BtxA) into 6 sites of left parotid after right parotidectomy *note controversial conclusions are statements marked by * and with bold italics. ![]() Selected articles from pubmed search 2009 – 2013 “Botulinum toxin and salivary gland” Abnormality Treated See also: Sialendoscopy Course LSU New Orleans Lectures (Hoffman) Feb 1-2, 2014īotox injection to salivary glands for hypersalivationīotulinum Toxin (Btx) use in salivary disorders Botulinum neurotoxin treatment of salivary gland disorders
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